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Kálmán Hideg Selected Research

pyrroline

8/2011Synthesis of N-substituted 3,5-bis(arylidene)-4-piperidones with high antitumor and antioxidant activity.
10/2007N-hydroxy-pyrroline modification of verapamil exhibits antioxidant protection of the heart against ischemia/reperfusion-induced cardiac dysfunction without compromising its calcium antagonistic activity.

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Kálmán Hideg Research Topics

Disease

11Neoplasms (Cancer)
01/2018 - 05/2010
6Ovarian Neoplasms (Ovarian Cancer)
04/2014 - 05/2010
4Alzheimer Disease (Alzheimer's Disease)
11/2017 - 01/2012
4Myocardial Infarction
05/2009 - 10/2005
4Ischemia
01/2009 - 10/2005
2Heart Failure
03/2013 - 09/2008
2Cardiotoxicity
11/2011 - 01/2007
2Carcinoma (Carcinomatosis)
11/2011 - 09/2010
2Infarction (Infarctions)
01/2009 - 10/2007
2Reperfusion Injury
08/2006 - 10/2005
1Tics (Tic)
01/2020
1Colonic Neoplasms (Colon Cancer)
03/2019
1Amyloid Plaque
01/2017
1Ascites
04/2014
1Pulmonary Hypertension
03/2013
1Ovarian Epithelial Carcinoma
07/2012
1Pathologic Processes
01/2012
1Prostatic Neoplasms (Prostate Cancer)
05/2010
1Hypertrophy
08/2009
1Fibrosis (Cirrhosis)
08/2009
1Vascular Remodeling
06/2009
1Hyperplasia
06/2009
1Hypoxia (Hypoxemia)
05/2009
1Cardiomegaly (Heart Hypertrophy)
09/2008
1Cardiomyopathies (Cardiomyopathy)
01/2007
1Myocardial Ischemia (Ischemic Heart Diseases)
08/2006

Drug/Important Bio-Agent (IBA)

10(3,5- bis((4- fluorophenyl)methylidene)- 1- ((1- hydroxy- 2,2,5,5- tetramethyl- 2,5- dihydro- 1H- pyrrol- 3- yl)methyl)piperidin- 4- one)IBA
01/2018 - 06/2009
5AntioxidantsIBA
11/2011 - 01/2007
4Proteins (Proteins, Gene)FDA Link
01/2018 - 06/2009
4Peptides (Polypeptides)IBA
11/2017 - 01/2012
3PiperidonesIBA
03/2019 - 05/2010
3CurcuminIBA
01/2018 - 11/2011
3Caspase 3 (Caspase-3)IBA
07/2012 - 05/2010
3Antineoplastic Agents (Antineoplastics)IBA
08/2011 - 05/2010
3Poly(ADP-ribose) Polymerase InhibitorsIBA
08/2009 - 10/2005
2nitroxylIBA
01/2020 - 05/2010
2Amyloid beta-PeptidesIBA
11/2017 - 12/2015
2Amyloid (Amyloid Fibrils)IBA
01/2017 - 01/2012
2Doxorubicin (Adriamycin)FDA LinkGeneric
11/2011 - 01/2007
2Pharmaceutical PreparationsIBA
11/2011 - 06/2009
2alpha,beta-diacryloxypropionic acid (DAPS)IBA
08/2011 - 05/2010
2pyrrolineIBA
08/2011 - 10/2007
2Verapamil (Calan)FDA LinkGeneric
01/2009 - 10/2007
2Isoproterenol (Isoprenaline)FDA LinkGeneric
09/2008 - 10/2005
22- ((2- piperidin- 1- ylethyl)thio)quinazolin- 4(3H)- oneIBA
09/2008 - 10/2005
1Warfarin (Coumadin)FDA LinkGeneric
01/2020
1Cytochrome P-450 CYP2C19IBA
01/2020
1bergamottinIBA
01/2020
1Ticlopidine (Ticlid)FDA LinkGeneric
01/2020
1EnzymesIBA
01/2020
1Cytochrome P-450 CYP3AIBA
01/2020
1Cytochrome P-450 CYP2C9IBA
01/2020
1Ketoconazole (Nizoral)FDA LinkGeneric
01/2020
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2018
1GadoliniumIBA
01/2017
1Peroxynitrous Acid (Peroxynitrite)IBA
03/2013
1Therapeutic UsesIBA
07/2012
1statticIBA
07/2012
1PlatinumIBA
07/2012
1Caspase 7IBA
07/2012
1Tyrosine (L-Tyrosine)FDA Link
07/2012
1FluorenesIBA
01/2012
1Free RadicalsIBA
01/2012
1Cisplatin (Platino)FDA LinkGeneric
11/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2010
1Messenger RNA (mRNA)IBA
09/2010
1Sterol Regulatory Element Binding Protein 1IBA
09/2010
1ErbB Receptors (EGF Receptor)IBA
09/2010
1Mitogen-Activated Protein Kinase 3IBA
09/2010
1Focal Adhesion Protein-Tyrosine KinasesIBA
09/2010
1Fatty Acid Synthases (Fatty Acid Synthase)IBA
09/2010
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
09/2010
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2010
1Hydroxylamine (Hydroxylamine Hydrochloride)IBA
05/2010
1Superoxides (Superoxide)IBA
05/2010
1TensinsIBA
06/2009
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
06/2009
1NF-kappa B (NF-kB)IBA
06/2009
1Matrix Metalloproteinases (MMPs)IBA
06/2009
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
05/2009
1N-hydroxypiperidineIBA
01/2009
1HO-4038IBA
01/2009
1CollagenIBA
09/2008
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
09/2008
1Glycogen Synthase Kinase 3 betaIBA
09/2008
1EnalaprilFDA LinkGeneric
09/2008
11- hydroxy- 2,2,5,5- tetramethyl- 2,5- diydro- 1H- pyrrole- 3- carboxylic acid (2- (3,4- dimethoxyphenyl)- 5- ((2- (3,4- dimethoxyphenyl)ethyl)methylamino)- 2- isopropylpentyl)amideIBA
10/2007
1CalciumIBA
10/2007
1AnthracyclinesIBA
01/2007
1Daunorubicin (Cerubidine)FDA LinkGeneric
01/2007
1AminesIBA
01/2007
1Reactive Oxygen Species (Oxygen Radicals)IBA
08/2006
1Trimetazidine (Vastarel)IBA
08/2006
1Nuclear Proteins (Protein, Nuclear)IBA
10/2005
1Mitogen-Activated Protein KinasesIBA
10/2005
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
10/2005

Therapy/Procedure

6Therapeutics
01/2014 - 05/2010
2Drug Therapy (Chemotherapy)
07/2012 - 11/2011
1Injections
11/2011
1Ligation
05/2009